Axxam and Symeresand have further consolidated their strategic relationship, providing integrated drug discovery and development services to clients around the world, by announcing the transfer of a library of approx. 80,000 lead-like compounds, Symegold, to Axxam for use in high-throughput screens.
The Symegold library was synthesised at Symeres, recently rebranded from MercachemSyncom, in the Netherlands, as part of the European Lead Factory (ELF) IMI-2 consortium, using state-of-the-art parallel synthesis and purification platforms available at the Nijmegen and Groningen sites. The design criteria for preparing this novel and unique compound collection were based on diverse lead-like properties and structural novelty, using proprietary, rigid, sp3-rich scaffolds synthesised in house via innovative chemistries.
The addition of the Symegold library from Symeres to Axxam’s innovative 325,000 compound AXXDIV4.0 library provides Axxam and Symeres' clients with a world-class selection of screening sets, accessible singly or combined, for small-molecule drug discovery via high-throughput screening.
Dr. Eelco Ebbers, CEO of Symeres, commented, "We are very happy to offer this premium screening collection - the result of significant intellectual and technical effort by our parallel and medicinal chemistry teams in the Netherlands - via our strategic alliance with Axxam. This library of unique compounds will be an excellent starting point for hit-finding programs. Because of our knowledge of the chemistry of these library compounds, we are also able to follow up with fast hit optimization, providing additional benefits for our customers. The combination of high-quality chemistry, ADME-Tox, state-of-the-art assay development and high-throughput screening expertise is now accessible to our clients around the world".
Dr. Stefan Lohmer, CEO of Axxam, added, "We are continuously enlarging our screening compound collection, which we are considering as a kind of living and evolving organism, with high-quality entries. Therefore, we are very pleased that we can add the unique Symegold collection from our strategic partner, Symeres, resulting in a world-class screening collection composed of more than 400,000 compounds, available now for our customer screening projects".
For more information: https://axxam.com/